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Scott Aaronson theoretical computer scientist at the Institute for Quantum Computing University of Waterloo, Canada The greatest innovation in computer science was to represent machines as nothing but strings of information. |
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Ian Abley architect and research engineer The brick made civilisation possible, and will continue to do so. |
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Professor Thomas M Addiscott soil scientist, computer modeller and science writer The Haber-Bosch process for the synthesis of ammonia allowing the production of nitrogen fertiliser. |
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Anjana Ahuja science columnist The Times Sanitation, vaccination and modern surgery are all worth celebrating. |
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Dr Hugh Aldersey-Williams writer and curator As a writer I find two of the greatest innovations to be the tea cosy and digestive biscuits. |
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Dr Roger Armour retired consultant surgeon and inventor of the Optyse Lens Free Ophthalmoscope When Helmholtz announced his invention of the ophthalmoscope in December 1850, he gave the healing professions a priceless gift which he refused to patent. |
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Branko R Babic inventor Modern life without electricity would be impossible and would return humanity to prehistoric modes of existence. |
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Dr Philip Ball consultant editor at Nature and science writer Arguably, the most useful innovations in chemistry are methods of chemical analysis. I know that this sounds almost irredeemably dull, but I can't help feeling that that is the way with truly useful innovations. |
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Michael Baum emeritus professor of surgery and visiting professor of medical humanities at University College London. Understanding breast cancer as a systemic disorder has led to better survival rates. |
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Gordon Bell principal researcher with the Microsoft eSciences Research Group, San Francisco The Big Bang occurred when processing, memory, and control (programming) all came together to create the stored program computer concept that was the basis of subsequent computer innovation. |
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Dr Jong Bhak director, Korean Bioinformation Center (KOBIC) Exchanging biological/scientific information via openfree hypertext servers will revolutionise the collaborative work of biology/science in the near future as much as the internet itself did to biology in the 1990s. |
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Dr Susan Blackmore writer, lecturer and broadcaster The electroencephalogram. It began the process of being able to peer inside a human brain and watch it actually working. |
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Bernhard Blauel architect, RIBA, Blauel Architects. The greatest innovation in my field is man’s ability to reach places where gravity is reduced to imperceptible levels. |
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Dr Sonja Boehmer-Christiansen reader in geography at the University of Hull I can think of a bad one: ever more people pontificate about science and especially 'global warming' without any real understanding of climate and how little we understand it. |
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David Bradley freelance science writer based in Cambridge, sciencebase.com Our knowledge of the inorganic chemistry of ammonia, lime and sulphuric acid. |
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Professor Vladimir Burdyuzha Astro Space Center, Lebedev Physical Institute, Moscow The discovery that dark energy was already boosting the expansion of the Universe as long as nine billion years ago. |
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Nick Bush business improvement consultant, BT Retail What makes the Internet a key innovation is the effect it is beginning to have on societal structures in business, politics and leisure. |
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Dr Marcus Chown cosmology consultant of New Scientist The greatest innovation in physics was the realisation that the fundamental reality that underpins the world is totally unlike the familiar, everyday world of our senses. |
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Dr Stuart Clark science journalist and author Changing the emphasis of astronomy from measuring stellar positions for navigation to investigating the physical nature of celestial objects. |
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Professor Peter Cochrane co-founder of ConceptLabs The invention of the triode vacuum tube in 1915 by Lee DeForest marks the beginning of the information technology revolution. |
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Phillip J Colquitt independent technical advisor The most important innovation I’ve seen, being involved in health care for 30 years, is the move from metal to plastic. |
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Quentin Cooper broadcaster Radio can bring you into instant contact with almost anyone on the planet in an unfettered unfiltered way |
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